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. Author manuscript; available in PMC: 2009 Apr 8.
Published in final edited form as: Vaccine. 2008 Feb 20;26(16):2020–2033. doi: 10.1016/j.vaccine.2008.02.009

Table 4.

Effect of different doses of formalin-inactivated WNV vaccine on IC challenge in wild type mice on day 60

Vaccination Challenge Dose WNV PFU # survived/total P value
Intramuscular route
Placebo 101 0/10
1 μl (104 PFU) 101 1/10 0.1
10 μl (105 PFU) 101 2/10 0.2
100 μl (106 PFU) 101 8/10 0.0003
Intraperitoneal route
Placebo 101 0/10
1 μl (104 PFU) 101 1/10 0.1
10 μl (105 PFU) 101 3/10 0.08
100 μl (106 PFU) 101 7/10 0.001

Eight week-old wild type mice were vaccinated with different doses of formalin-inactivated WNV vaccines through the indicated routes. Mice were challenged 60 days after immunization with 101 PFU of WNV New York by an IC route and monitored for survival for 28 days. P values were determined using log rank test.