Table 1.
5′ | A | G | U | C | 3′ | ||||
---|---|---|---|---|---|---|---|---|---|
A | AAA | Phe | AGA | Ser | AUA | Tyr | ACA | Cys | |
G | GAA | Phe | GGA | Ser | GUA | Tyr | GCA | Cys | A |
U | UAA | Leu | UGA | Ser | UUA | Stop | UCA | Stop | |
C | CAA | Leu | CGA | Ser | CUA | Stop | CCA | Trp | |
A | AAG | Leu | AGG | Pro | AUG | His | ACG | Arg | |
G | GAG | Leu | GGG | Pro | GUG | His | GCG | Arg | G |
U | UAG | Leu | UGG | Pro | UUG | Gln | UCG | Arg | |
C | CAG | Leu | CGG | Pro | CUG | Gln | CCG | Arg | |
A | AAU | Ile | AGU | Thr | AUU | Asn | ACU | Ser | |
G | GAU | Ile | GGU | Thr | GUU | Asn | GCU | Ser | U |
U | UAU | Ile | UGU | Thr | UUU | Lys | UCU | Arg | |
C | CAU | Met | CGU | Thr | CUU | Lys | CCU | Arg | |
A | AAC | Val | AGC | Ala | AUC | Asp | ACC | Gly | |
G | GAC | Val | GGC | Ala | GUC | Asp | GCC | Gly | C |
U | UAC | Val | UGC | Ala | UUC | Glu | UCC | Gly | |
C | CAC | Val | CGC | Ala | CUC | Glu | CCC | Gly | |
G2-C71 | C2-G71 |
Boxed areas are amino acids activated by class I aaRSs, and shaded areas are those activated by class II aaRSs. The vertical line divides the table into two halves in accordance with the consensus second base pair (shown below) in the acceptor helix of corresponding tRNAs when they are recognized by the opposite aaRSs (see text and Fig. 1 for detail).