Figure 1 Effects of heat exposure (43°C) on TCO, MAP, HR, CBF, the extracellular concentrations of glutamate, glycerol and NO, and the lactate/pyruvate ratio in rat brain in different groups. Points are mean (SEM) for eight rats per group. NT, rats kept normothermic (24°C); HE, rats kept at 43°C for 55 min; HS, heat stroke onset; SED, sedentary rats; 3wk1D, 1 day after 3‐week‐exercise‐training group; TB, blanket temperature; TCO, colonic temperature; MAP, mean arterial pressure; HR, heart rate; CBF, cerebral blood flow; NOx, nitric oxide metabolite. *p<0.05 compared with the SED+NT group. †p<0.05 compared with the SED+HE group (analysis of variance for repeated measures, followed by Duncan's test).