Table 2 Consumption of anabolic androgenic steroids consumption increased the frequency of micronucleated cells from buccal mucosa in bodybuilders.
| Cases | Sampling week | |||||
|---|---|---|---|---|---|---|
| 1st | 2nd | 3rd | 4th | 5th | 6th | |
| Group 1 (with no AAS consumption) | ||||||
| 1 | 0.5 | 1.5 | 1.0 | 0.5 | 0.5 | 0 |
| 2 | 0.5 | 0 | 0.5 | 0 | 0 | 1.0 |
| 3 | 0.5 | 0 | 0 | 0 | 0 | 0 |
| 4 | 1.0 | 0.5 | 0.5 | 0.5 | 1.0 | 1.0 |
| 5 | 0.5 | 1.0 | 1.0 | 0.5 | 0 | 0 |
| 6 | 0 | 0 | 0 | 1.0 | 0 | 0 |
| Mean (SD)/week | 0.5 (0.3) | 0.5 (0.6) | 0.5 (0.4) | 0.4 (0.3 | 0.2 (0.4) | 0.3 (0.5) |
| Mean (SD)/group | 0.4 (0.4) | |||||
| p Value* | NS | NS | NS | NS | NS | |
| Group 2 (with AAS consumption) | ||||||
| 1 | 1.3 | 9.0 | 10 | 8.5 | 5.5 | 6.8 |
| 2 | 1.3 | 4.5 | 6.5 | 5.5 | 5.5 | 4.0 |
| 3 | 1.0 | 3.5 | 4.0 | 3.5 | 2.5 | 1.5 |
| 4 | 1.0 | 4.5 | 4.5 | 5.5 | 3.5 | 1.0 |
| 5 | 1.0 | 2.5 | 4.5 | 6.3 | 3.5 | 2.0 |
| Mean (SD)/week | 1.1 (0.1) | 4.8 (2.4) | 5.9 (2.4) | 5.8 (1.8) | 4.1 (1.3) | 3.0 (2.3) |
| Mean (SD)/group | 4.1 (2.4) | |||||
| p Value† | 0.043 | 0.042 | 0.043 | 0.041 | NS | |
| p Value‡ | 0.030 | 0.004 | 0.004 | 0.004 | 0.004 | 0.009 |
| p Value§ | 0.001 | |||||
Results are presented as micronucleated cells per 1000 cells.
AAS, anabolic androgenic steroids.
Comparisons were made per week: intragroup (1st sampled week vs weeks 2–6; *group 1; †group 2) and ‡intergroup (treated group weeks vs the corresponding control group week). §Comparison between MNC mean per group (group 1 vs group 2).