Table 2.
Clinical and pathologic features.
| Solitary N = 1053 | Multifocal N = 60 | ||
|---|---|---|---|
| Feature | N (%) | P-value | |
| Age at Surgery (years) | |||
| <65 | 554 (52.6) | 23 (38.3) | .031 |
| ≥65 | 499 (47.4) | 37 (61.7) | |
| Sex | |||
| Female | 339 (32.2) | 11 (18.3) | .025 |
| Male | 714 (67.8) | 49 (81.7) | |
| Symptoms at presentation | |||
| Absent | 582 (55.3) | 39 (65.0) | .140 |
| Present | 471 (44.7) | 21 (35.0) | |
| Constitutional symptoms at presentation | |||
| Absent | 893 (84.8) | 49 (81.7) | .512 |
| Present | 160 (15.2) | 11 (18.3) | |
| ECOG Performance status (N = 903) | |||
| 0 | 749 (88.4) | 50 (89.3) | .846 |
| ≥1 | 98 (11.6) | 6 (10.7) | |
| Type of Surgery | |||
| Open radical nephrectomy | 532 (50.5) | 41 (68.3) | .007 |
| Open nephron-sparing surgery | 460 (43.7) | 16 (26.7) | |
| Laparoscopic radical nephrectomy | 23 (2.2) | 3 (5.0) | |
| Laparoscopic nephron-sparing surgery | 38 (3.6) | 0 | |
| 2002 Primary tumor classification | |||
| pT1a | 1020 (96.9) | 59 (98.3) | 1.00 |
| pT3a | 20 (1.9) | 1 (1.7) | |
| pT3b | 11 (1.0) | 0 | |
| pT3c | 2 (0.2) | 0 | |
| RCC Nuclear grade | |||
| 1 | 147 (14.0) | 6 (10.0) | .672 |
| 2 | 673 (63.9) | 40 (66.7) | |
| 3 | 221 (21.0) | 14 (23.3) | |
| 4 | 12 (1.1) | 0 | |
| Coagulative tumor necrosis | |||
| Absent | 921 (87.5) | 54 (90.0) | .562 |
| Present | 132 (12.5) | 6 (10.0) | |
| Sarcomatoid Differentiation | |||
| Absent | 1048 (99.5) | 60 (100.0) | 1.00 |
| Present | 5 (0.5) | 0 | |