Table 2 Familial standardised incidence ratios for subtypes of nerve, nerve root and plexus disorders when sibling was diagnosed with any of these diseases.
Subtypes in offspring | Men | Women | All | |||
---|---|---|---|---|---|---|
O | SIR (95% CI) | O | SIR (95% CI) | O | SIR (95% CI) | |
Disorders of the trigeminal nerve | 6 | 2.78 (0.71 to 8.61) | 9 | 1.88 (0.60 to 5.07) | 15 | 2.16 (0.85 to 5.05) |
Trigeminal neuralgia | 4 | 2.51 (0.46 to 9.20) | 7 | 2.28 (0.64 to 6.68) | 11 | 2.36 (0.83 to 5.99) |
Facial nerve disorders | 17 | 2.48 (1.02 to 5.64) | 13 | 1.54 (0.58 to 3.73) | 30 | 1.96 (0.94 to 3.97) |
Bell's palsy | 16 | 2.61 (1.05 to 6.01) | 13 | 1.73 (0.65 to 4.18) | 29 | 2.12 (1.00 to 4.32) |
Disorders of other cranial nerves | 3 | 10.41 (1.39 to 43.56) | 0 | 3 | 1.97 (0.26 to 8.25) | |
Nerve root and plexus disorders | 9 | 1.89 (0.60 to 5.09) | 12 | 2.08 (0.76 to 5.15) | 21 | 1.99 (0.87 to 4.31) |
Disorders of the brachial plexus | 3 | 1.12 (0.15 to 4.70) | 5 | 2.30 (0.51 to 7.64) | 8 | 1.65 (0.50 to 4.62) |
Mononeuritis of the upper limb and mononeuritis multiplex | 39 | 3.73 (1.87 to 7.21) | 55 | 3.17 (1.69 to 5.84) | 94 | 3.38 (1.93 to 5.85) |
Carpal tunnel | 11 | 5.28 (1.85 to 13.41) | 30 | 3.77 (1.80 to 7.62) | 41 | 4.08 (2.07 to 7.84) |
Ulnar nerve | 15 | 3.32 (1.31 to 7.76) | 11 | 2.09 (0.73 to 5.30) | 26 | 2.66 (1.23 to 5.51) |
Radial nerve | 6 | 2.75 (0.70 to 8.52) | 8 | 3.92 (1.18 to 10.97) | 14 | 3.31 (1.28 to 7.88) |
Mononeuritis of the lower limb | 6 | 1.14 (0.29 to 3.54) | 22 | 3.42 (1.51 to 7.32) | 28 | 2.39 (1.12 to 4.90) |
Meralgia paresthetica | 2 | 5.51 (0.37 to 28.63) | 2 | 1.54 (0.10 to 8.02) | 4 | 2.41 (0.44 to 8.81) |
Lateral poplitean nerve | 1 | 0.88 (0.00 to 7.10) | 5 | 8.03 (1.79 to 26.71) | 6 | 3.40 (0.87 to 10.54) |
Plantar nerve | 1 | 1.78 (0.00 to 14.44) | 4 | 8.41 (1.55 to 30.76) | 5 | 4.82 (1.08 to 16.04) |
All types | 80 | 2.69 (1.51 to 4.73) | 111 | 2.52 (1.47 to 4.30) | 191 | 2.59 (1.58 to 4.22) |
O, observed number of cases; SIR, standardised incidence ratio.
Bold face : 95% CI does not include 1.