Figure 3.

Nucleotide and deduced amino acid sequence of the IL-16 precursor cDNA. The two possible initiation codons are underlined. The ATG that was originally believed to mark the beginning of the 390 bp IL-16 coding region is marked by a black bar. The previously published 5′ end of the IL-16 cDNA is shown by an arrow. The location of the splice junction where in some cDNAs short intervening sequences have been found is identified by a triangle. The positions of the putative proteolytic cleavage site at aspartate residue 510 (nucleotide position 1,708), and the codon GCA (alanine) at nucleotide position 1,759, which is absent in some IL-16 splice variants, are underlined. The 3′-UTR is not shown.