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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Arch Biochem Biophys. 2008 May 1;475(2):175–183. doi: 10.1016/j.abb.2008.04.034

Table 2.

Percent low and high spin CYP2C9 enzyme in the presence of flurbiprofen and/or dapsone

Enzyme (+ substrate) % Low Spin % High Spin
CYP2C9.1 (no substrate) 96.0 4.00
+ Flurbiprofen 84.3 15.7
+ Flurbiprofen and Dapsone 73.2 26.8
+ Dapsone 88.7 11.3
CYP2C9.2 (no substrate) 94.8 5.24
+ Flurbiprofen 88.8 11.2
+ Flurbiprofen and Dapsone 74.3 25.7
+ Dapsone 86.1 13.9
CYP2C9.3 (no substrate) 96.9 3.14
+ Flurbiprofen 87.1 12.9
+ Flurbiprofen and Dapsone 75.5 24.5
+ Dapsone 90.8 9.19
CYP2C9.5 (no substrate) 92.9 7.15
+ Flurbiprofen 89.8 10.2
+ Flurbiprofen and Dapsone 86.5 13.5
+ Dapsone 86.4 13.6