Table 2.

Volumetric and proton spectroscopy measurements in autistic and normal control subjects

Thalamic Measurements	Autistics		Control		t-test
	n = 18		n = 16		df = 32
	Mean	S.D.	Mean	S.D.	t	P
Volume (cc)
Left Thalamus	3.9	0.5	3.9	0.3	0.506	0.616
Right Thalamus	4.1	0.6	4.1	0.4	−0.099	0.922
Total Brain Volume	1352.2	129.8	1341.7	90.3	0.271	0.788
1H MRS
Left NAA	4.4	1.4	5.6	1.0	−2.923	0.006
Left PCr+Cr	2.7	0.9	3.6	1.0	−2.400	0.022
Left GPC+PC	0.9	0.3	1.2	0.2	−3.088	0.004
Left Myo-Inositol	2.5	0.9	3.0	0.6	−1.682	0.102
Left Glutamate + Glutamine	7.21	2.93	8.75	1.91	−1.795	0.082
Right NAA	4.9	1.84	5.6	1.1	−1.224	0.230
Right PCr+Cr	3.3	1.3	3.6	0.9	−0.813	0.422
Right GPC+PC	1.1	0.4	1.2	0.3	−1.449	0.157
Right Myo-Inositol	2.8	1.2	2.8	0.9	0.061	0.951
Right Glutmate+ Glutamine	7.60	2.96	7.67	1.76	−0.084	0.934

Metabolite concentration expressed in absolute values; NAA: N-Acetylaspartate; PCr+Cr: creatine + phosphocreatine; GPC+PC: glycerophosphocholine + phosphocholine