Figure 11.

Quality of the phases obtained by exploiting the AAS-induced symmetry-breaking effects in IMPDH. The plots represent the correlation coefficients, as a function of resolution, of maps computed from experimental phases with a map computed from the final refined structure of IMPDH. Black, SAD phases computed from merged data with conventional isotropic f′ and f′′ factors. Red, SAD phases computed from unmerged data using a tensorial parametrization ( + ) to describe AAS. Green, two-wavelength MAD (peak + inflection point) phases computed from merged data with conventional isotropic f′ and f′′ factors. Blue, three-wavelength MAD phases computed from merged data with conventional isotropic f′ and f′′ factors. Orange, three-wavelength MAD phases computed from unmerged data using a tensorial parametrization ( + ) to describe AAS.