Figure 2.
Stereographic superimposition of Fc/TM with the CD16-liganded human Fc structure corresponding to PDB code 1e4k (Sondermann et al., 2000 ▶). Superimposition of Cα atoms of Fc/TM and 1e4k (CH2 domain residues 236–342) was carried out using LSQKAB (Kabsch, 1976 ▶). For both chains of 1e4k, the r.m.s. displacement was estimated at 1.9 Å, with a maximum displacement of 6.4 Å for the Cα of residue 286. Human CD16 and Fc/TM are colored green and orange, respectively. Chains A and B of 1e4k are colored red and blue, respectively.