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. 2008 May 16;51(7):1139–1145. doi: 10.1007/s10350-008-9328-y

Table 2.

Overview of studies concerning the influence of the level of arterial ligation on anastomotic circulation

Study Level of evidence Design N Procedure Outcome measure Results
Seike et al. (2007)31 2b Prospective cohort 96 Rectal cancer resection with high tie Tissue blood flow Significant blood flow reduction after high techniques; high blood flow reduction in older, male patients
Dworkin et al. (1996)29 2b Prospective cohort 26 Rectosigmoid resection Tissue blood flow Significant blood flow reduction after IMA ligation
Hall et al. (1995)28 2b Prospective cohort 62 Colorectal resection with high or low tie Tissue oxygen tension No significant difference; tissue oxygen tension of sigmoid not adequate after both techniques
Kashiwagi et al. (1994)30 2b Prospective cohort 13 IMA clamping Tissue blood flow No significant reduction
Corder et al. (1992)18 2b Retrospective cohort 143 Rectal resection with high or low tie Anastomotic leakage rate No significant differences

IMA = inferior mesenteric artery.