Table 3.
Thioredoxin-linked mitigation of the allergic response to the Osborne fractions
| Protein, ng | %
mitigation
|
|||
|---|---|---|---|---|
| Gliadins | Glutenins | Albumins | Globulins | |
| Highly sensitive dog | ||||
| 30 | 53 | 17 | 33 | 27 |
| 10 | 66 | 20 | 44 | 0 |
| 3 | 100 | 62 | 69 | 66 |
| 1 | 100 | 100 | 46 | 100 |
| 0.3 | 100 | 100 | — | — |
| Mildly sensitive dog | ||||
| 300 | 50 | 100 | 33 | 75 |
| 100 | 10 | 100 | 0 | 100 |
| 30 | 78 | 100 | — | — |
| 10 | 100 | — | — | — |
Percent mitigation is defined as the wheal area of the control minus that observed after treatment divided by that of the control times 100. Dogs B and C, were used for the highly and mildly sensitive dogs, respectively (see Table 1).