Figure 1.

Alignment of SA11 VP4 sequence to the α2β1 integrin ligand site (underlined) in type 1 collagen. The sequences show 27% identity. Stars indicate identical amino acids, dots indicate conserved amino acids, and both symbols refer to the relatedness of the named sequence to SA11. ▾, The amino acid positions at which mutations were found in escape mutants selected with neutralizing mAbs (6, 7, 30).