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Effects of propranolol on the changes in PI hydrolysis and cAMP formation caused by NE treatment. PI hydrolysis and cAMP formation were significantly increased by 1-h treatment with NE (50 μM). Coincubation with propranolol (50 μM) inhibited the increase in cAMP formation caused by NE (∗, P < 0.05) but had no effect on the increase in PI hydrolysis. The graph represents means and SEM obtained from three independent experiments.
