Figure 3.

Square-well potential with a desolvation barrier representing the hydrophobic-pair potential between pairs of beads participating in native contacts in the Gō model. We parameterize the pressure dependence of the model potential by ɛ⁺ = 1.333 + .2778P, and ɛ⁻ = −1.00 + .1667P, where P is in kbar. At P = 0, the contact-well depth is −1, and the desolvation barrier from the solvent-separated configuration is 1.333. Here the units of energy have been chosen for convenience so that the relevant temperatures are of order one. Energies are shown in units of temperature.