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Effect of treatment with GHRH antagonist JV-1-36 on tumor volume and weight in nude mice bearing xenografts of H-69 human SCLC
| Treatment | Initial tumor volume, mm3 | Final tumor volume, mm3 | Tumor burden, mg tumor wt/g body wt |
|---|---|---|---|
| Control | 64.8 ± 10.1 | 2,254 ± 584 | 64.7 ± 15.1 |
| JV-1-36 (10 μg/day) | 66.1 ± 15.9 | 1,036 ± 337 | 35.7 ± 12.5 |
| JV-1-36 (20 μg/day) | 65.1 ± 12.7 | 461 ± 91* | 17.7 ± 4.2* |
*P < 0.05.
