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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Curr Opin Genet Dev. 2008 Feb 21;18(1):97–106. doi: 10.1016/j.gde.2007.12.001

Figure 1.

Figure 1

General and specific structures of activity-based probes (ABPs) (A) General structure of an ABP. (B) DCG-04 is an ABP that targets cysteine proteases and contains a biotin tag (red), a dipeptide-containing linker (blue), and an epoxide as a warhead (green). FP-rhodamine is an ABP that targets the serine hydrolase superfamily of enzymes and contains a rhodamine fluorophore (red), a poly(ethylene glycol) linker (blue), and a fluorophosphonate as a warhead (green).