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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Curr Opin Genet Dev. 2008 Feb 21;18(1):97–106. doi: 10.1016/j.gde.2007.12.001

Table 1.

Enzyme classes characterized using ABPs.

ABP ABP structure Proteome Enzyme activity References
FP-rhodamine graphic file with name nihms54340t1.jpg Human breast melanoma cell lines
Human ER(+) and ER(−) breast tissue samples
HT-hi/diss and HT-low/diss human fibrosarcoma cell lines MDA-MB-231 breast cancer cells before and after passage in mice		 Serine hydrolases 18, 19, 20, 29
FP-biotin graphic file with name nihms54340t2.jpg Human ER(+) and ER(−) breast cancer tissue samples
HT-hi/diss and HT-low/diss human fibrosarcoma cell lines		 Serine hydrolases 19, 20
HxBP-Rh graphic file with name nihms54340t3.jpg Human melanoma cell lines
Human breast cancer cell lines		 Metalloproteases 17, 22
SAHA-BPyne graphic file with name nihms54340t4.jpg Human melanoma and breast cancer cell lines Class I/II HDACs 24
HAUb-VME graphic file with name nihms54340t5.jpg Cervical carcinoma biopsies tissue samples and cell lines
Human tumor cell lines		 USPs 25, 27
DCG-04 graphic file with name nihms54340t6.jpg PyMT/ctsb+/+, PyMT/ctsb−/−, and PyMT/ctsb+/− murine tumor cells RIP1-TAG2 murine normal and tumor cells Cysteine cathepsins 28, 42, 43
Phenyl-SE graphic file with name nihms54340t7.jpg MDA-MB-231 breast cancer cells before and after passage in mice
Human breast cancer cell lines		 Multiple enzymes, including thiolases, sugar kinases, and glutathione S-transferases 29, 30, 31, 32
GB137 graphic file with name nihms54340t8.jpg Human and mouse tumor cell lines
MDA-MB-231 xenografted breast cancer cell lines from mice		 Cysteine cathepsins 49