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. Author manuscript; available in PMC: 2008 Jul 16.
Published in final edited form as: Eur J Neurosci. 2006 Jun;23(11):2983–2990. doi: 10.1111/j.1460-9568.2006.04845.x

Fig. 4.

Fig. 4

Intraterminal calcium levels increase with duration of the test step (−70 to −10 mV). Calcium levels (ΔF/F) were measured using the dye Oregon Green 488 BAPTA 5N at the hot spot in rod terminals. In control conditions, calcium levels (filled squares and solid line, n = 7) increased abruptly when the step was lengthened from 100 to 200 ms, accompanying the spread of calcium through the terminal illustrated in Figs 2 and 3. Introducing ryanodine (25 μM, open squares and dashed line, n = 5) into rods through the patch pipette abolished the abrupt increase in calcium levels measured at the hot spot, in addition to inhibiting the secondary spread evoked by longer steps as shown in Fig. 5.