Table 2.
Chromosome aberrations in spontaneously immortalized cells
| Cell type | No. cells scored | Gaps, breaks, and deletions | Total exchange-type aberrations | Telomeric fusions | ITS* | TF per cell | Chromosomes per cell† |
|---|---|---|---|---|---|---|---|
| WT (p34) | 50 | 52 | 7 | 0 | 0 | 0.000 | 73.3 ± 3.7 |
| scid (p28) | 50 | 12 | 226 | 225 | 1 | 4.50 | 71.2 ± 5.2 |
| scid (p35) | 50 | 13 | 264 | 254 | 8 | 5.08 | 74.0 ± 3.1 |
| p53−/− (p26) | 50 | 17 | 28 | 0 | 0 | 0.000 | 65.7 ± 7.5 |
| p53−/−/scid (p23) | 50 | 26 | 69 | 58 | 3 | 1.16 | 57.5 ± 8.4 |
*ITS, interstitial telomeric sequence.
†Average number of chromosomes per cell ± SD.