Table 3.
Chromosome aberrations in virally transformed cells
| Cell type | No. cells scored | Gaps, breaks, and deletions | Total exchange-type aberrations | Telomeric fusions | ITS* | TF per cell | Chromosomes per cell |
|---|---|---|---|---|---|---|---|
| WT | 100 | 19 | 16 | 0 | 0 | 0.000 | 62.8 ± 7.6 |
| Ku 70−/− | 76 | 20 | 50 | 8 | 0 | 0.105 | 54.6 ± 5.1 |
| Ku 80−/− | 61 | 13 | 118 | 8 | 0 | 0.131 | 74.4 ± 9.1 |
| SC-A1 | 50 | 13 | 68 | 54 | 10 | 1.08 | 56.5 ± 6.6 |
| SC-EM | 50 | 21 | 95 | 89 | 3 | 1.78 | 57.5 ± 6.2 |
| SC-A1 (p + 6)† | 50 | 14 | 55 | 19 | 21 | 0.380 | 57.3 ± 6.5 |
| SC-EM (p + 6) | 50 | 41 | 81 | 70 | 5 | 1.40 | 57.0 ± 4.8 |
*ITS, interstitial telomeric sequence.
†Reexamination six passages later.