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. 2008 Jul 3;9:60. doi: 10.1186/1471-2350-9-60

Table 3.

Genes in which a SNP has a p-value < 0.01 for the maternal-fetal incompatibility model in the pre-eclampsia dataset

Gene Symbol rs Number Incompatibility model P-value Additive Model P-value % of Incompatibility Odds Ratio1 95% CI1


Maternal effects Fetal effects Cases Controls
LTA 2857713 0.0007 0.53 0.67 29.6 35.1 0.439 [0.273, 0.708]
IGF1R 28401726 0.0017 0.42 0.23 11.7 8.54 3.089 [1.530, 6.238]
VWF 216900 0.0037 0.15 0.86 28.9 17.9 2.104 [1.273, 3.480]
VWF 216321 0.0083 0.17 0.59 24.6 19.6 1.940 [1.185, 3.176]
COL4A2 2296849 0.0046 0.01 0.03 24.5 16.2 2.193 [1.274, 3.773]
COL4A2 421177 0.0054 0.02 0.22 32.2 23.2 1.952 [1.219, 3.125]
IGF1 5742620 0.0088 0.01 0.48 8 3.65 3.504 [1.371, 8.955]
IL2RA 10752175 0.0082 0.09 0.22 44.7 34.9 1.797 [1.163, 2.777]

1Model unadjusted for Maternal and Fetal Effects