Table 1.
Characteristics | Mild1 | Severe | Fisher's exact test | ||
Age (median years, 25–75%) 2 | 39, 28–48 | 37, 23–53 | |||
Sex (M:F) (Patient Number) | 7:13 | 26:13 | |||
DENV-1: DENV-3 (Patient Number) | 20:0 | 8:31 | p < 0.0001 | ||
%3 | N4 | % | N | ||
Fever | 30 | 20 | 8 | 37 | |
Haemorrhagic manifestations5 | 35 | 20 | 41 | 37 | |
Petechia | 21 | 19 | 49 | 37 | |
Abdominal Pain | 19 | 16 | 33 | 36 | |
Thrombocytopenia (<100.000 counts/mm3) | 63 | 19 | 72 | 39 | |
Thrombocytopenia (<50.000 counts/mm3) | 0 | 19 | 46 | 39 | |
Hipotension6 | 0 | 20 | 67 | 39 | |
Hemoconcentration7 | 33 | 15 | 10 | 39 | |
Secondary Infection | 26 | 19 | 42 | 33 | P = 0.37 |
1 See Methods for mild and severe dengue definition.
2 Study population with 59 patients with 3–10 days of disease onset.
3 Percentage of positive patients for the measured parameter within the group.
4 Number of patients used for the measured parameter within the group.
5 Epistaxis, gengivorrhagia, positive tourniquet test, metrorrhagia, bleeding after coughing.
6Postural hypotension with decrease in systolic arterial pressure in 20 mmHg in supine position or systolic arterial pressure < 90 mmHg.
7 Elevated hematocrit for matched age and sex (women>41%; men >45%) or fluctuation of packed cell volume ≥ 20% during course of illness and recovery.