Table 2.

Logistic models with logit links for different clinical manifestations and laboratorial assays during dengue fever based on cytokine production.

Severity1 Yes = 39, No = 20 3	Coefficient	Error	P value (significance)4	OR2 (CI 95% range)
Intercept	10.855	4.150	0.0089**	-
Log (MIP-1β +1e-4) -	1.712	0.705	0.0153*	0.181(0.045–0.72)
Log (IFN-γ +1e-4)	0.130	0.046	0.0046**	1.138 (1.041–1.245)
Platelet counts 50.000/mm3 Yes = 18 No = 40	Coefficient	Error	P value (significance)	OR (CI 95% range)
Intercept	0.940	0.943	0.3187	-
MIP-1β	-0.010	0.023	0.0057**	0.990 (0.983–0.997)
IL-1β	0.056	0.023	0.0123*	1.058 (1.012–1.106)
TNF-α	-0.022	0.008	0.0100*	0.978(0.962–0.995)
MCP-1	0.002	0.001	0.0437*	1.002 (1.0001–1.0036)
Hypotension Yes = 24 No = 35	Coefficient	Error	P value (significance)	OR (CI 95% range)
Intercept	0.357	0.742	0.6302	-
IL-1β	0.075	0.038	0.0454*	0.928 (0.862–0.999)
IL-12	0.005	0.012	0.6516	1.006 (0.982–1.030)
IL-13	-0.013	0.014	0.3519	0.987 (0.960–1.015)
MIP-1β	-0.004	0.002	0.0807	0.996 (0.992–1.000)
MCP-1	0.001	0.0007	0.2065	1.001 (0.9995–1.002)
GM-CSF	0.0043	0.0017	0.0214*	1.004 (1.001–1.007)

¹Models were chosen according to their best Akaike information criterion (AIC). In this model we used MIP-1β and IFN-γ log values in order to obtain a small AIC.

²OD, odds ratio; CI, confidence interval.

³Number of patients.

⁴ * P < 0.05, ** P < 0.01 and *** P < 0.001.