Table 4.

The areas under curve for proteolytic enzymes, CEA and CA 19-9 according to ROC curves.

Variable	AUC	Lower limit	Upper limit
PAI-1	0.9385	0.9025	0.9744
CATB	0.8665	0.7934	0.9397
uPA	0.7143	0.6091	0.8196
CATL	0.6173	0.5158	0.7188
CA 19-9	0.4990	0.3937	0.6043
CEA	0.4748	0.3690	0.5807

Determination of areas under curve for cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 according to ROC curves allowing to evaluate their accuracy and different discriminative power

Abbreviations: AUC: area under curve; CATB: cathepsin B; CATL: cathepsin L; uPA: urokinase-type plasminogen activator, PAI-1: plasminogen activator inhibitor type-1; CEA: carcinoembryonic antigen; CA 19-9: carbohydrate antigen 19-9; ROC: receiver operating characteristics