Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Jul 23;3(7):e2770. doi: 10.1371/journal.pone.0002770

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

A. IP3 activation in PC-IN population after onset of a PF signal. Each PC-IN pair is assumed to have one main time constant that generates an IP3 profile. The curves show IP3 activations by a PF signal that continued throughout the displayed time period (1500 ms). For clarity, every fourth IP3 component used in the simulation is displayed. It is assumed that the distribution of the peak time has a broad Gaussian distribution with a center around 300 ms, thus having a relatively denser representation at early timing. B. An example of one shared IP3 peak latency (in red) and two small variations (in blue and green) inside of a PC-IN pair. C. A cartoon explanation of the IP3 latencies. In this example, the PC has an IP3 peak latency of 300 ms (red) shared with the IN dendrite. A variation of IP3 peak latencies at 200 ms (green) and 400 ms (blue) are assigned to the other two spines. Note that in this example only the 300 ms peak latency is shared by the PC and IN (red).