Table 2.
Stage-Related Melanosome Proteins (Partial List)
| Stages | UniProtKB | Gene Name | Protein Name | Notes∗ |
| P36955 | PEDF | Pigment epithelium-derived factor precursor | ||
| P51148 | RAB5C | Ras-related protein Rab-5C (RAB5L) (L1880) | Validated | |
| P05556 | ITGB1 | Integrin beta-1 | ||
| Stage I | ||||
| Q9UMX9 | Matp | Membrane-associated transporter protein (SLC45A2) | Homolog | |
| O14880 | MGST3 | Microsomal glutathione S-transferase 3 | ||
| Proposed | ||||
| Q14254 | FLOT2 | Flotillin-2 (Epidermal surface antigen) | ||
| Q9UMX9 | Matp | Membrane-associated transporter protein (SLC45A2) | ||
| Homolog | ||||
| Q04656 | ATP7A | Copper-transporting ATPase 1 | ||
| Stage II | Q9P0L0 | VAPA | Vesicle-associated membrane protein-associated protein A | |
| P53992 | SEC24C | Protein transport protein Sec24C | Proposed | |
| O95782 | AP2A | Adapter-related protein complex 2 alpha- 1 subunit | ||
| O95670 | ATP6G2 | Vacuolar ATP synthase subunit G 2 | ||
| Validated | ||||
| Q71RS6 | SLC24A | Sodium/potassium/calcium exchanger 5 precursor | ||
| P57729 | Rab-38 | Ras-related protein Rab-38 | ||
| P51159 | RAB27A | Ras-related protein Rab-27A (Rab-27) | ||
| Homolog | ||||
| Q9Y4I1 | Myo5a | Myosin-5A (Myosin Va) | ||
| Stage IV | Q99698 | LYST | Lysosomal trafficking regulator | |
| Q16643 | DBN1 | Drebrin | ||
| P59998 | ARPC4 | Actin-related protein 2/3 complex subunit 4 | ||
| P18206 | VCL | Vinculin (Metavinculin) | Proposed | |
| P63000 | RAC1 | Ras-related C3 botulinum toxin substrate 1 (p21-Rac1) | ||
| P51148 | RAB5C | Ras-related protein Rab-5C (RAB5L) |
∗
All proteins listed are identified in the melanosome proteomes. Validated –shown to be localized in melanosomes by immunostaining; Homolog – homologous to known mouse coat color genes; Proposed – proposed as protein of functional interest for validation.