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. Author manuscript; available in PMC: 2008 Nov 8.
Published in final edited form as: Nature. 2007 Nov 8;450(7167):219–232. doi: 10.1038/nature06340

Figure 8. Scaling of discovery power with the number and distance of informant species.

Figure 8

a, Discriminatory power of CSF protein-coding evolutionary metric for varying exon lengths and using different numbers of informant species. Sensitivity is shown for known exons at a fixed false-positive rate based on random non-coding regions. Mean length is shown for each exon length quantile. Multi-species comparisons increase discovery power, especially among short exons. b, Recovery of known ncRNAs (among the top 100 predictions) for pairwise (blue) and multi-species (red) comparisons. c, Recovery of cloned miRNAs (among the top 100 predictions). d, Recovery of transcription factor and miRNA motifs with instances at 60% confidence.

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