Figure 4. Reduced expression of PPARγ and its target lipogenic enzymes in the liver of ISR-defective Alb::GC transgenic mice on a high fat diet.

A–E. Relative levels of PPARγ, FASN, ACACβ, ACACα, and SCD1 mRNA in liver of non-transgenic (WT) and Alb::GC transgenic mice in the fasted state or fed a low (LFD and high fat diet) (mean ± SEM, n=3–4, *p<0.05).