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. Author manuscript; available in PMC: 2008 Jul 18.
Published in final edited form as: Epilepsy Res. 2007 Mar 26;74(2-3):116–125. doi: 10.1016/j.eplepsyres.2007.02.003

Fig. 5.

Fig. 5

Blood and brain concentration profiles for constant infusion dosing of 3-MPA: (A) average blood 3-MPA concentration (n = 9 rats); (B) average brain 3-MPA concentration in striatum (n = 16 rats); (C) representative plot displaying ECoG recording with the corresponding brain 3-MPA concentration superimposed. The 3-MPA was administered at t = 0 min. The boxes in each plot (t = 20−50 min) represent the time when a steady-state concentration of 3-MPA was achieved in the brain. The arrow represents the time in which the infusion was stopped.