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. Author manuscript; available in PMC: 2008 Jul 18.
Published in final edited form as: Indian J Med Res. 2007 May;125(5):619–632.

Table I.

Burden of rotavirus disease in hospitalized children

Centre Year of study Age (yr) Testing method Samples
Tested Positive
n n %
North India:
Chandigarh16 1982 - 1985 <5 ELISA 694 111 15.9
Delhi17 1987 - 1989 <5 ELISA 978 176 18.0
Delhi18 1987 - 1988 <5 ELISA 288 44 15.3
Delhi19 1988 - 1990 <5 ELISA 990 104 10.5
Delhi20 1989 - 1990 <3 Immunodot 400 23 6.0
Delhi21 1990 - 1991 <5 ELISA/PAGE 450 60 13.3
Delhi22 1990 <5 ELISA 157 71 45.0
Delhi23 1998 - 2000 <5 ELISA/PAGE 1172 158 13.5
Delhi24 2000 - 2001 <5 ELISA 584 137 23.5
Delhi25 1998 - 2000 <3 ELISA/PAGE 560 100 17.8
North India26 NK NK ELISA 172 32 19.0
Western India:
Bombay27 1984 - 1986 NK LA /EM / ELISA 273 63 21.0
Pune28 1990 - 1993 children ELISA 722 188 26.0
Pune29 1992 - 1996 <5 ELISA 945 266 28.2
Eastern India:
Dibrugarh30 1999 - 2000 <5 ELISA 202 47 23.3
South India:
Bangalore31 1988 - 1994 NK PAGE 694 150 21.6
Chennai32 1997 - 1999 0 - 2, >2 ELISA 245 51 20.8
Chennai33 1995 - 1999 <3 ELISA 745 168 22.6
Hyderabad34 1998 - 1999 <2 PAGE 352 57 16.2
Manipal35 NK <5 LA 106 19 18
Mysore31 1993 - 1994 NK PAGE 447 50 11.2
Tirupati36 1991 <2 ELISA 170 40 23.5
Vellore37 1995 - 1998 <5 ELISA / LA 602 126 20.9
Vellore38 2002 - 2004 <5 ELISA/ LA 343 94 27.1
Multiple**:
Multiple 139 1993 6m to <5 ELISA 458 63 13.7
Multiple 240 1996 - 1998 <5 ELISA 1502 313 20.8
Multiple 341 1998 - 1999 <5 LA /EM / ELISA 365 82 22.5
Multiple 442@ 1998 - 2000 <4 PAGE 406 141 34.7
Multiple 543# 2001 <4/all# PAGE 454 161 35.4
Total 15476 3095

NK, not known

#

<4/all: Samples collected from two groups: children <4 yr, patients of all age groups

LA, latex agglutination; EM, electron microscopy; PAGE, polyacrylamide gel electrophoresis; ELISA, enzyme linked immunosorbent assay.

**

Multiple studies in which samples were collected from more than one city.

Multiple 1: Shimla, Lucknow, Bhopal, Nagpur, Davengere

Multiple 2: Shimla, Lucknow, Bhopal, Nagpur, Davengere, Delhi, Hyderabad

Multiple 3: Vellore, Mysore, Jalandhar, Yamunagar

Multiple 4: Kolkata, Imphal, @ Data on disease burden from Kolkata only

Multiple 5: Kolkata, Dibrugarh, Bhuvaneshwar, Chandigarh