Table 1.

Significantly increased interleukin-6 and interleukin-10 levels in the cerebrospinal fluid

	serum		CSF
day	1	8	1	8
IL-6	7.9	4.2	20	3.5
IL-4	3.2	<2.6	<2.6	<2.6
IL-2	<2.6	<2.6	<2.6	<2.6
IFN-γ	<7.1	<7.1	<7.1	<7.1
TNF-α	2.8	<2.8	<2.8	<2.8
IL-10	7.5	2.9	<2.8	<2.8
				pg/ml

Cytokine assay study of blood serum and cerebrospinal fluid at the time points of pre- and post-treatment with methylprednisolone. In the patient's serum, interleukin-6 and interleukin-10 were elevated at day 1 (pre-treatment) and decreased at day 8 (post-treatment). In his cerebrospinal fluid, interleukin-6 levels were remarkably high (19.6 pg/ml) at day 1 and reduced to normal levels by day 8.