Fig. 3.

Influence of beta-carotene on gene expression in HUVEC. The expression of selected genes verified by the quantitative real-time PCR. CXCR4 (chemokine (C-X-C motif ) receptor 4), IL-8 (interleukin 8); VCAM-1 (vascular cell adhesion molecule 1); MAD1L1 (MAD1 mitotic arrest deficient-like 1); MEOX2 (mesenchyme homeo box 2 (growth arrest-specific homeo box)); EGR-1 (early growth response 1) and BIRC5 (baculoviral IAP repeat-containing 5) apoptosis inhibitor. Data expressed as relative gene expression calculated versus control (HUVECs incubated in medium with 0.075%THF/EtOH). The mean values ± SEM ; significance P < 0,05 at least , n = 3 done in triplicates are shown