Table 2. Sperm counts of mice with various allele combinations.
# Genotype | Sperm/ml* | % abnormal Sperm^ |
---|---|---|
1 repro5/+ | 1.3×106 | 6% |
2 repro5/+ | 8.0×105 | 6% |
3 Gt/+ | 1.0×106 | 4% |
4 +/+ | 1.3×106 | 8% |
5 Gt/+ | 9.0×105 | 11% |
Avg | 1.0×106 | 7% |
6 repro5/repro5 | 5.0×104 | 98% |
7 repro5/repro5 | 5.0×104 | 97% |
Avg | 5.0×104 | 97.5% |
8 repro5/Gt | 2.0×105 | 65% |
9 repro5/Gt | 1.7×105 | 96% |
Avg | 1.85×105 | 81% |
10(Gt/Gt | 3.3×105 | 81% |
1 Gt/Gt | 1.9×105 | 86% |
1;Gt/Gt | 4.5×105 | 95% |
Avg | 3.2×105 | 87.3% |
Sperm concentration was determined by mincing 1 epididymis into 2 ml of PBS, and counting after 1 hour.
The percentage of abnormal sperm was determined by counting 100 sperm from each mouse. The following groups of animals were littermates: (1,2,6,7); (3,11,12); (4,5,8,9). Animals 10 was sired by the same parents as 11 & 12. All males were 2–4 months of age.