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. 2008 Jul 30;3(7):e2840. doi: 10.1371/journal.pone.0002840

Figure 2. Permanent effects of neonatal novelty exposure on social competitive success and stress response system function (24 months of age).

Figure 2

AB. When trained individually, Novel and Home rats showed no difference in learning to obtain chocolate rewards nor did they differ in final level of performance (N Novel = 11, N Home = 11). C. During paired social competition testing, Novel rats won significantly more rewards than Home rats on Day 1 but not on Day 2 (N = 11 pairs of Novel and Home rats). D. Novel but not Home rats exhibited a significant reduction in wins from Day 1 to Day 2. E. Despite a significant difference between Novel and Home rats in wins on Day 1, there was no parallel difference in post-competition corticosterone (CORT) concentration. Overall, CORT response to social competition significantly decreased across testing days (N = 14 pairs of Novel and Home rats). F. Novel but not Home rats exhibited significant habituation of CORT response across days. In all panels, data are mean±SEM; * indicates p<0.05; ns indicates p>0.05.