TABLE 2.
Age-adjusted ORs for CVD Associated with a 1 SD Increase in WC or BMI
|
Age-adjusted ORs for Diabetes Associated with a 1 SD Increase in WC or BMI
|
|||||||
---|---|---|---|---|---|---|---|---|
Men
|
Women
|
Men
|
Women
|
|||||
Region | WC | BMI | WC | BMI | WC | BMI | WC | BMI |
NW Europe | 1.29(1.23–1.36)* | 1.27(1.21–1.33)* | 1.37(1.30–1.44)* | 1.31(1.24–1.37)* | 1.76(1.67–1.86)* | 1.72(1.63–1.81)* | 2.17(2.05–2.29)* | 1.96(1.86–2.06)* |
S Europe | 1.31(1.25–1.38)* | 1.22(1.17–1.28)* | 1.30(1.23–1.37)* | 1.22(1.16–1.28)* | 1.45(1.38–1.53)* | 1.39(1.33–1.46)* | 1.78(1.69–1.87)* | 1.68(1.60–1.76)* |
E Europe | 1.42(1.35–1.49)* | 1.41(1.34–1.48)* | 1.48(1.42–1.54)* | 1.53(1.47–1.59)* | 1.83(1.72–1.95)* | 1.73(1.63–1.83)* | 1.98(1.88–2.09)* | 1.82(1.73–1.91)* |
N Africa | 1.48(1.25–1.74)* | 1.51(1.30–1.77)* | 1.50(1.28–1.75)* | 1.52(1.32–1.74)* | 1.57(1.38–1.79)* | 1.57(1.38–1.78)* | 1.63(1.46–1.82)* | 1.44(1.30–1.60)* |
S Africa | 1.93(1.49–2.50)* | 1.63(1.29–2.06)* | 1.51(1.19–1.92)† | 1.43(1.11–1.84)‡ | 1.71(1.38–2.11)* | 1.52(1.25–1.85)* | 1.89(1.52–2.34)* | 1.70(1.38–2.09)* |
Middle East | 1.44(1.25–1.66)* | 1.49(1.30–1.70)* | 1.51(1.28–1.79)* | 1.52(1.29–1.78)* | 1.35(1.22–1.50)* | 1.40(1.27–1.54)* | 1.86(1.64–2.11)* | 1.89(1.68–2.12)* |
E Asia | 1.33(1.21–1.47)* | 1.32(1.20–1.46)* | 1.32(1.22–1.44)* | 1.21(1.12–1.30)* | 1.38(1.25–1.51)* | 1.25(1.14–1.37)* | 1.45(1.33–1.57)* | 1.32(1.23–1.43)* |
S Asia | 1.27(1.18–1.36)* | 1.26(1.17–1.35)* | 1.30(1.21–1.39)* | 1.26(1.18–1.35)* | 1.53(1.44–1.62)* | 1.43(1.35–1.51)* | 1.57(1.47–1.67)* | 1.41(1.33–1.50)* |
Australia | 1.76(1.39–2.22)* | 1.53(1.24–1.89)* | 1.19(0.95–1.50) | 1.11(0.87–1.40) | 1.49(1.20–1.85)† | 1.50(1.22–1.83)† | 1.45(1.20–1.75)† | 1.54(1.28–1.86)* |
Canada | 1.26(1.08–1.47)‡ | 1.19(1.03–1.39)§ | 1.50(1.25–1.81)* | 1.49(1.25–1.77)* | 1.92(1.65–2.23)* | 1.81(1.57–2.09)* | 2.40(2.06–2.80)* | 2.02(1.76–2.32)* |
Latin America | 1.28(1.19–1.38)* | 1.23(1.15–1.32)* | 1.36(1.28–1.44)* | 1.37(1.29–1.44)* | 1.36(1.27–1.46)* | 1.34(1.26–1.43)* | 1.66(1.57–1.75)* | 1.51(1.44–1.59)* |
Overall | 1.36(1.33–1.39)* | 1.32(1.29–1.35)* | 1.40(1.37–1.43)* | 1.38(1.35–1.41)* | 1.59(1.56–1.63)* | 1.52(1.49–1.56)* | 1.83(1.79––1.87)* | 1.67(1.64–1.71)* |
P<0.0001;
P<0.001;
P<0.01.
P<0.05
BMI indicates body mass index; CI, confidence interval; CVD, cardiovascular disease; OR, odds ratio; SD, standard deviation; WC, waist circumference.
Data are age-adjusted ORs (95% CI) for CVD and for diabetes for an increase of 1 SD (region-specific) in WC or BMI (see Table 1 for SDs by region and overall). Overall data are also adjusted for region.