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. Author manuscript; available in PMC: 2008 Jul 20.
Published in final edited form as: Fertil Steril. 2007 Aug 13;89(6):1795–1802. doi: 10.1016/j.fertnstert.2007.05.046

Table 2.

Crude and adjusted odds ratio estimates from conditional logistic regression models of risk of miscarriage.

Unadjusted models Adjusted model a
OR [95% CI] OR [95% CI]
Th1-type cytokines b IL-1β 0.90 [0.77, 1.05] 0.76 [0.59, 0.97]
IFN-γ 1.01 [0.87, 1.18] 1.09 [0.91, 1.30]
TNF-α 0.92 [0.79, 1.08] 0.93 [0.77, 1.13]
Th2-type cytokines b IL-1ra 1.01 [0.89, 1.14] 1.06 [0.90, 1.24]
IL-4 1.00 [0.86, 1.17] 1.05 [0.88, 1.25]
IL-6 0.99 [0.86, 1.15] 1.19 [0.96, 1.48]
Growth factors b G-CSF 0.84 [0.72, 0.99] 0.78 [0.64, 0.95]
TPO 1.09 [0.95, 1.25] 1.16 [1.00, 1.36]

Abbreviations: IL, interleukin; RA, receptor antagonist; G-CSF, granulocyte colony stimulating factor; IFN, interferon; TNF, tumor necrosis factor; TPO, thrombopoietin

a

Adjusted model included terms for all cytokines, maternal age, and gestational age at sample collection

b

Biomarkers were standardized by dividing assay-determined concentration by the standard deviation among controls