Table 3.
Dissociation constants of complexes of G′2 quadruplex integrin DNA with unmodified and chimerical MyoD and Myogenin homodimers
| Protein homodimer | Kd (nM) of protein-G′2 integrin DNA complex [N] |
|---|---|
| Myogenin | 30.0 ± 8.0 [4] |
| Myogenin/MyoDb chimera | 7.1 ± 1.9 [4] |
| MyoD | 4.4 ± 2.5 [10] |
| MyoD/Myogeninb chimera | 6.0 ± 3.1 [5] |
Dissociation constants, Kd, of protein–DNA complexes were determined as described under Materials and methods section and in the legends to Figures 1 and 2. Shown are average Kd values ± SD with [N] denoting the number of independent measurements of each value.