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. 2008 May 30;36(12):e71. doi: 10.1093/nar/gkn287

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — NFκB inhibition effect on the p3NF-luc-3NF nuclear import. HeLa cells were incubated with a mixture of Cy3-p3NF-luc-3NF polyplexes (hatched bar) and fluo-pTAL-luc polyplexes (grey bar) made with LPEI (A) or HIS (B) in the presence of BAY 11-7085 and TNFα. Cells were also transfected in the absence of BAY 11-7085 with Cy3-p3NF-luc-3NF polyplexes (solid bar) and fluo-pTAL-luc polyplexes (open bar). Results are the mean value of 12 nuclei. (asterisk) Significant statistical difference of values obtained between cells tranfected with p3NF-luc-3NF in the absence or the presence of BAY 11-7085 according to a Student's test with P < 0.01.