Skip to main content
. 2008 Aug 8;4(8):e1000124. doi: 10.1371/journal.pcbi.1000124

Table 1. Base pair distance between the sampled and native structures for cis-regulatory elements from Hepatitis C virus and HIV.

RNA #seq length #bp 0 1 2 3 4 5
HCV CRE 52 51.0 14 1.8/0 2.7/0 6.1/2 8.6/1 10.8/9 12.4/10
HCV SLIV 110 35.0 15 0.3/2 0.3/1 0.3/1 0.3/1 0.3/1 0.3/1
HIV PBS 388 94.8 17 12.3/4 14.9/5 16.7/1 17.6/1 18.3/1 -
HIV FE 853 51.9 10 7.6/1 7.7/2 7.7/2 7.6/2 7.4/2 7.2/2
HIV GSL3 1403 81.1 8 9.3/0 9.1/0 8.9/0 9.2/0 9.6/0 -

Native structure is here taken as the Rfam consensus structure from the seed alignments of these elements of HCV and HIV. Two measures are given. The average distance represents the average base pair distance between sampled structures and the native secondary structure S 0. The centroid represents the average base pair distance between sampled structures and the sample centroid S c, where the latter is defined to consist of those base pairs occurring in strictly more than half the sampled structures. The number of sequences in the Rfam seed alignment, the average length and the number of basepairs in the native structure are given before the average and centroid distance values.