Figure 1.

Urinary protein excretion (A), urinary albumin excretion (B), and blood pressure (C) in Dahl SS and SHR rats. As expected, SHR rats remained non-proteinuric throughout the time course of the study. Dahl SS rats developed proteinuria and albuminuria between 4 and 6 weeks of age (A and B). In Dahl SS rats, measurements were taken at an additional time point, 5 weeks of age, to obtain a more detailed view of the early phase of proteinuria development in these rats. Both rat strains developed hypertension starting at week 8. At 10 weeks of age, the blood pressure of SHR rats was significantly higher than that of Dahl SS rats (C). An asterisk indicates P < 0.05.