Skip to main content
. 2008 Aug;173(2):385–399. doi: 10.2353/ajpath.2008.070729

Figure 7.

Figure 7

TGF-β enhances FAK protein expression at the level of transcription in Caco-2 and IEC-6 cells. A: Activity of the FAK promoter-luciferase construct, normalized to Renilla and expressed as percentage of the respective nontreated control, is significantly higher in IEC-6 and Caco-2 cells 24 hours after TGF-β treatment (*P = 0.007 versus nontreated respective control, n = 4 for each). B: FAK mRNA levels are higher in IEC-6 cells as early as 2 hours after treatment with TGF-β. RT-PCR results, normalized to the 18S control, are expressed as fold increase over nontreated control cells (*P < 0.05, n = 5).