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Connectivity of the NAc with other brain regions such as prefrontal cortex, ventral tegmental area (VTA). Activity of the NAc is mainly regulated by dopaminergic (from VTA) and glutamatergic afferents (from frontal cortex, amygdala and hippocampus). In addition, inputs of GABAergic, serotonergic (from raphe) and adrenergic afferents (from locus ceruleus) as well as cholinergic interneuons (within the NAc) also modified activity of the NAc.
