Table 2.

Comparison of honeybee receptors with vertebrate receptors and characteristics of these honeybee receptors.

Honeybee receptor (endogenous agonist)	Most closely related vertebrate receptor class	Effect of activation	Occurrence in the brain	References
AmDOP1 (DA)	DA D1/D5 receptors	cAMP↑	ubiquitously	[12, 88, 114]
AmDOP2 (DA)	1-adrenergic receptors	cAMP↑	restricted to the mushroom bodies	[73, 88, 114]
AmDOP3 (DA)	DA D2 receptors	cAMP↓	ubiquitously	[4]
AmTYR1 (TA)	α2-adrenergic receptors/5-HT1 receptors	cAMP↓	ubiquitously	[13, 116]
AmOA1 (OA)	α1-adrenergic receptors	Ca2+↑	ubiquitously	[48, 58]