Table 2.
Marker | No. of subjects | Survival time, weeks
|
χ2‡ | P value | Corrected P value | ||
---|---|---|---|---|---|---|---|
75%† | 50%† | 25%† | |||||
Total | 83 | 31 | 38 | 45 | |||
D6Mit15-D7Mit12-D17Mit7 | |||||||
N-N : N-N : N-N | 11 | 34 | 39 | 44 | |||
N-N : N-N : N-S | 13 | 29 | 39 | 46 | |||
N-N : N-S : N-N | 9 | 44 | 56 | 68 | |||
N-N : N-S : N-S | 6 | 27 | 32 | 45 | 25.22 | 5.1 × 10−8 | 3.7 × 10−5 |
N-S : N-N : N-N | 10 | 29 | 32 | 45 | |||
N-S : N-N : N-S | 14 | 24 | 31 | 32 | |||
N-S : N-S : N-N | 5 | 40 | 42 | 44 | |||
N-S : N-S : N-S | 15 | 36 | 39 | 47 | |||
D6Mit15 (74.0 cM) | |||||||
N-N | 39 | 32 | 41 | 55 | |||
N-S | 44 | 30 | 33 | 40 | 8.70 | 0.0032 | 0.094 |
D7Mit12 (66.0 cM) | |||||||
N-N | 48 | 29 | 32 | 41 | |||
N-S | 35 | 37 | 42 | 56 | 8.49 | 0.0036 | 0.11 |
D17Mit7 (27.3 cM) | |||||||
N-N | 35 | 34 | 41 | 55 | |||
N-S | 48 | 29 | 33 | 44 | 3.56 | 0.0593 | 0.89 |
N-N, homozygous NIH/Ola Mus spretus; N-S, heterozygous NIH/Ola Mus spretus.
†75%, 50%, and 25% indicate the percentage of mice alive until the time (in weeks) after initiation.
‡χ2 values were obtained by the Cox regression method.