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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Exp Neurol. 2008 Apr 3;212(1):108–117. doi: 10.1016/j.expneurol.2008.03.019

Fig. 4.

Fig. 4

Quantification of astroglia within 600 μm of the infusion site; GFAP/TUNEL immunolabeling. Dark nuclei are TUNEL (+). A. 3 day IgG infusion and B. 3 day flk-1-NA have comparable numbers of astrocytes adjacent to the wound sites (W). C. 3 day flt-1-NA infusion shows a slightly decreased astroglial population compared to A and B. D, E. After 7 days, IgG and flk-1-NA infusions show large numbers of GFAP(+) reactive astrocytes near the wound area, while in F, flt-1-NA administration exhibited markedly reduced numbers of reactive astrocytes. Bar = 100 μm. G. Counts of astrocyte numbers at infusion sites. A statistically significant decrease in astrocytes was detected at 7 days only with flt-1-NA infusions compared to IgG controls. *P < 0.05 (vs. control). Error bars represent SEM.