Table 1.
Clinical features of the patient group.
| Whole group n = 424 | Decline group n = 110 | Emphysema | Bronchiectasis | Chronic bronchitis | ||||
| Yes n = 279 | No n = 70 | Yes n = 83 | No n = 266 | Yes n = 159 | No n = 265 | |||
| Gender (% male) | 59.91 | 66.36 | 64.16 | 54.29 | 57.83 | 63.67 | 64.78 | 57.03 |
| Age (years) | 50.01 (0.52) | 51.48 (0.92) | 51.76 (0.78) | 41.52 (33.77–49.27) | 54.18 (1.03) | 48.90 (0.63) | 50.79 (0.77) | 49.48 (0.69) |
| Pack years | 14.00 (2.35–25.65) | 18.75 (9.01–28.49) | 17.50 (7.65–27.35) | 0 (0–4.18) | 14.63 (4.33–25.93) | 13.50 (1.40–24.60) | 14.63 (2.55–26.71) | 12.75 (0.75–24.75) |
| FEV1 %predicted | 37.15 (18.30–56.04) | 35.01 (18.25–51.77) | 32.08 (18.94–45.22) | 102.88 (80.93–124.83) | 36.64 (14.59–58.69) | 35.54 (17.39–53.69) | 32.76 (15.49–50.03) | 38.17 (14.18–62.16) |
| FEV1/FVC | 38.40 (25.95–50.85) | 37.30 (27.10–48.40) | 35.00 (26.00–44.00) | 73.60 (63.10–84.10) | 40.10 (24.35–55.85) | 37.50 (25.00–48.00) | 37.85 (26.85–48.85) | 39.40 (26.40–52.40) |
| KCO %predicted | 69.82 (1.18) | 68.09 (2.12) | 63.18 (1.38) | 98.66 (2.55) | 67.85 (2.75) | 70.57 (1.54) | 67.62 (2.31) | 71.34 (1.89) |
| UZVI | 31.09 (1.05) | 32.84 (1.69) | 32.71 (1.02) | 2.31 (0.39) | 33.45 (1.89) | 30.63 (1.27) | 32.98 (1.69) | 29.88 (1.36) |
| LZVI | 44.59 (1.21) | 52.10 (38.53–65.68) | 46.78 (1.14) | 5.85 (1.01) | 54.15 (39.50–68.80) | 47.95 (32.15–63.75) | 48.85 (34.60–63.10) | 49.50 (31.90–67.10) |
| Decline of FEV1 (ml/yr) | 31.3 (4.1) | |||||||
Data is presented as mean (SEM) or median (IQR) dependent on its distribution. UZVI = upper zone voxel index, LZVI = lower zone voxel index. The only significant difference between the decline group and the whole dataset was that they had smoked more (p = 0.01).