Table 1.
Expression patterns of FUS, EWS and TAF15 in human tissues by TMA immunohistochemistry analysis
| FUS | EWS | TAF15 | |||||
| Organ | Tissue/Cell type | Nuclear | Cytoplasmic | Nuclear | Cytoplasmic | Nuclear | Cytoplasmic |
| Adrenal gland | Parenchymal cells | +++ | +++ | +++ | - | +++ | +++ |
| Appendix | Appendix smooth muscle | +++ | +++ | +++ | - | +++ | +++ |
| Brain | |||||||
| - white matter | Glial cells | +++ | - | +++ | - | +++ | - |
| - grey matter | Neurons | +++ | + | +++ | - | +++ | + |
| Breast | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Myoepithelial cells | +++ | +++ | ++ | - | +++ | +++ | |
| Endothelium, capillaries | +++ | ++ | +++ | - | +++ | +++ | |
| Adipocytes | +++ | - | +++ | - | +++ | - | |
| Colon & Rectum | Surface epithelium | +++ | +++ | ++ | - | +++ | +++ |
| Crypt epithelium | +++ | +++ | ++ | - | +++ | +++ | |
| Malt tissue, germinal centre | +++ | - | +++ | - | +++ | - | |
| Malt tissue, mantle zone | +++ | - | +++ | - | ++ | - | |
| Duodenum | Enterocytes, villus epithelium | +++ | +++ | ++ | - | +++ | +++ |
| Enterocytes, crypt epithelium | +++ | +++ | ++ | - | +++ | +++ | |
| Ganglion cells | +++ | +++ | +++ | - | +++ | +++ | |
| Endometrium | |||||||
| - proliferative | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Stromal cells | +++ | - | ++ | - | +++ | - | |
| - secretory | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Stromal cells | ++ | - | ++ | - | ++ | - | |
| Esophagus | Squamous epithelium, suprabasal | +++ | +++ | +++ | - | +++ | +++ |
| Squamous epithelium, basal | ++ | +++ | + | - | ++ | +++ | |
| Endothelium, medium-sized arteries | +++ | + | +++ | - | +++ | ++ | |
| Smooth muscle cells | +++ | +++ | +++ | - | +++ | +++ | |
| Gallbladder | Mucosal epithelium | +++ | +++ | +++ | +++ | +++ | +++ |
| Smooth muscle cells | +++ | +++ | +++ | - | +++ | +++ | |
| Heart | Cardiac muscle cells | - | - | - | - | - | - |
| Cardiac endothelium | - | - | ++ | - | - | - | |
| Kidney | Glomeruli | ++ | - | ++ | - | ++ | - |
| Proximal tubuli | +++ | +++ | +++ | +++ | +++ | +++ | |
| Distal tubuli | +++ | +++ | +++ | +++ | +++ | +++ | |
| Liver | Hepatocytes | - | +++ | ++ | +++ | - | +++ |
| Bile duct epithelium | +++ | +++ | +++ | +++ | +++ | +++ | |
| Lung & Bronchus | Respiratory epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ | |
| Pneumocytes | ++ | - | ++ | - | ++ | + | |
| Chondrocytes | +++ | - | ++ | - | ++ | - | |
| Endothelium, capillaries | +++ | - | +++ | - | +++ | - | |
| Muscle artery, endothelial cells | +++ | - | +++ | - | +++ | - | |
| Muscle artery, smooth muscle | +++ | +++ | +++ | - | +++ | +++ | |
| Lymph node | Germinal centre | ++ | - | ++ | - | ++ | - |
| Mantle zone | ++ | - | ++ | - | ++ | - | |
| Myometrium | Smooth muscle cells | + | - | + | - | + | - |
| Nasal mucosa | Respiratory epithelium | +++ | ++ | ++ | - | +++ | ++ |
| Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ | |
| Ovary | Follicular epithelium | +++ | +++ | ++ | - | +++ | +++ |
| Ovarial stromal cells | +++ | - | +++ | - | +++ | - | |
| Pancreas | Exocrine glands | +++ | +++ | +++ | - | +++ | +++ |
| Duct epithelium | +++ | +++ | +++ | - | +++ | +++ | |
| Endocrine cells | +++ | +++ | +++ | +++ | +++ | +++ | |
| Placenta | Syncytiotrophoblasts | ++ | ++ | + | + | ++ | +++ |
| Cytotrophoblasts | +++ | + | ++ | + | +++ | + | |
| Prostate | Prostate epithelium | + | + | ++ | + | ++ | + |
| Basal cells | +++ | - | +++ | - | ++ | - | |
| Salivary gland | Serous cells | +++ | +++ | +++ | ++ | +++ | +++ |
| Mucous cells | +++ | + | ++ | - | +++ | + | |
| Intercalated/striated ducts | +++ | +++ | +++ | +++ | +++ | +++ | |
| Myoepithelium | +++ | - | +++ | - | +++ | - | |
| Salpinx | Glandular epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Seminal vesicle | Epithelium | +++ | +++ | +++ | +++ | +++ | +++ |
| Skeletal muscle | Skeletal muscle fibers | ++ | - | ++ | - | +++ | - |
| Skin & Subcutis | Keratinocytes | +++ | +++ | +++ | - | +++ | +++ |
| Melanocytes | - | - | - | - | - | - | |
| Fibroblasts | +++ | - | +++ | - | +++ | - | |
| Ecrine epithelium, sweat gland | +++ | +++ | ++ | - | +++ | +++ | |
| Endothelium, capillaries | +++ | - | +++ | - | +++ | - | |
| Adipocytes | +++ | - | ++ | - | ++ | - | |
| Spleen | Lymphocytes, red and white pulp | ++ | - | ++ | - | + | - |
| Stomach | |||||||
| - body | Surface & foveolar epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Specialized glandular epithelium | + | +++ | + | +++ | + | +++ | |
| - antrum | Surface & foveolar epithelium | +++ | +++ | ++ | - | +++ | +++ |
| Specialized glandular epithelium | +++ | +++ | ++ | - | +++ | ++ | |
| - smooth muscle | Smooth muscle cells | +++ | - | +++ | - | +++ | - |
| Small bowel | Enterocytes, villus epithelium | +++ | +++ | ++ | - | +++ | +++ |
| Enterocytes, crypt epithelium | +++ | +++ | ++ | - | +++ | +++ | |
| Ganglion cells | +++ | +++ | +++ | +++ | +++ | +++ | |
| Testis | Germinal epithelium | +++ | - | +++ | - | +++ | - |
| Leydig intestitial cells | ++ | ++ | ++ | - | ++ | +++ | |
| Spermatides | + | - | + | - | ++ | - | |
| Thymus | T-lymphocytes | ++ | - | ++ | - | ++ | - |
| Epithelium | +++ | + | +++ | - | +++ | +++ | |
| Thyroid | Follicular epithelium | +++ | +++ | ++ | - | +++ | +++ |
| Tonsil | Squamous cell epithelium | +++ | +++ | +++ | - | +++ | +++ |
| Lymphocytes | +++ | - | +++ | - | +++ | - | |
| Umbilical cord | Stromal cells | +++ | ++ | ++ | - | +++ | ++ |
| Urinary bladder | Urothelium | +++ | +++ | +++ | - | +++ | +++ |
| Uterine cervix | Squamous epithelium, basal | +++ | +++ | ++ | - | +++ | +++ |
| Squamous epithelium, suprabasal | +++ | +++ | +++ | - | +++ | +++ | |
The percentage of FET positive cells within an organ is indicated as: +++ (100-76% positively staining cells), ++ (75-26% positively staining cells), + (25-1% positively staining cells) and - (negative).