Figure 1.

Persistent injury of Plg^o livers after CCl₄. (Upper) Plg⁺ livers have a diffuse pale/lacy appearance 2 days after CCl₄, followed by restoration of normal appearance by days 7 and 14 (arrows point to residual areas of abnormal appearance). (Lower) In contrast, although the same diseased appearance is seen in Plg^o livers on day 2, absence of plasminogen leads to a persistent diseased appearance at days 7 and 14. Although not depicted in the figure, Plg^o livers on days 30 and 70 resemble those on day 14.